Reduction of disease-related mortality

The ability of medications to reduce symptoms and improve quality of life make it reasonable to ask if patients' lives can be extended.

Current evidence suggests that smoking cessation, long-term oxygen therapy in hypoxaemic patients, noninvasive mechanical ventilation in some patients with acute-on-chronic respiratory failure, and lung volume reduction surgery improve survival. The TORCH (TOwards a Revolution in COPD Health) study also showed a reduction in the relative risk of dying over 3 years (although not statistically significant).1


  1. Calverley PMA, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007;356:775-89.

Inflammation in COPD

Learn more about the central role of inflammation in COPD.Go

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