Most patients require oxygen supplementation. Supplemental oxygen should be titrated to improve the patient’s hypoxia, with a target saturation of 88–92%. Patients whose condition deteriorates with oxygen therapy (e.g. those with severe acidaemia or CNS depression) require ventilatory assistance.1


  1. Global Initiative for Chronic Obstructive Lung Disease (GOLD): Global Strategy for the Diagnosis, Management, and Prevention of COPD. 2013. www.goldcopd.org

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